Effect of thiamine on the excretion of subcutaneously injected lead in rats.

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Title:	Effect of thiamine on the excretion of subcutaneously injected lead in rats.
Author:	Ito, Y : Niiya, Y : Otani, M : Shima, S
Citation:	Toxicol-Lett. 1987 Aug; 37(3): 221-8
Abstract:	The effect of thiamine on the excretion of lead in feces was investigated using rats injected subcutaneously with lead acetate and thiamine pyrophosphate. The amount of lead excreted increased with the amounts of thiamine administered, while lead concentrations in blood, liver and femur also increased. The amount of lead excreted in feces decreased, however, with administration of oxythiamine and vanadium. These results suggest that excretion of lead in feces is enhanced by thiamine and that it promotes evacuation of lead from the body.
Review References:	None
Notes:	None
Language:	English
Publication Type:	Journal-Article
Keywords:	Organometallic Compounds metabolism : Thiamine pharmacology
URL:	http://www.elsevier.com/inca/publications/store/5/0/5/5/1/9/index.htt